The Science Behind rmvd. The Science Behind rmvd.

The mechanism, the ingredients, and the published studies.

  • Expert Formulated
  • No Proprietary Blends
  • Lab Tested
Jump to the studies ↓

Three Key Jobs,
All Done Together

rmvd was made to work with normal digestion rather than against it: binding particles first, keeping things moving second, then supporting the gut lining & microbiome for the long haul. rmvd was made to work with your normal digestion: binding particles first, keeping things moving second, then supporting the gut lining & microbiome for the long haul.

  • PHASE 1

    Bind

    Chitosan, a fiber derived from crustacean shells, forms a gel in the stomach that can trap dietary microplastic particles alongside food as it's digested.

  • PHASE 2

    Move

    Magnesium oxide and ginger root extract support regular motility, so bound particles are carried through and cleared rather than sitting in the gut.

  • PHASE 3

    Support

    Sodium butyrate, zinc bisglycinate, and the LactoSpore probiotic strain support the intestinal lining and microbiome that stand between exposure and absorption.*

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Microplastics are everywhere

They are in the water you drink, the food you eat & the air you breathe.

Avoiding them completely is virtually impossible, so we built rmvd to help support your body's ability to pass them naturally - while supporting your gut lining and microbiome along the way.*

THE SCIENCE
Scientific measurements comparing microplastics in organs, 2016 to 2024.
Liver Brain
Microplastics concentration (µg g⁻¹) 10,000 1,000 100 10 0.001 0.0127 Liver Liver Brain Brain 2016 2024 2016 2024
Microplastics in organs, 2016 vs 2024.
Liver
Conc. (µg g⁻¹) 10,000 1,000 100 10 2016 2024
Microplastic accumulation in liver tissue
Brain
Conc. (µg g⁻¹) 10,000 1,000 100 10 2016 2024
Microplastic accumulation in brain tissue

Our Microplastic Advisory Board

Clinicians and researchers who have come together to help join the fight against microplastics.

Physician, Anatomic & Clinical Pathology

Dr. Abbas is a licensed physician specializing in anatomic and clinical pathology. His work centers on disease diagnosis, tissue pathology, and multidisciplinary cancer care, giving him a deep understanding of disease processes at the cellular and tissue level. He brings deep expertise in precision medicine and diagnostics, with a focus on translating pathologic findings into actionable clinical decisions.

Physician & Neurovascular Researcher

Dr. Matus is a physician and researcher with experience in cerebrovascular physiology, neuroscience, medical imaging, and human vascular health. His academic work has included research at Mayo Clinic and Semmelweis University, with a focus on cerebral blood flow, vascular disease, neurological outcomes, and the complex interactions between circulation, the brain, and overall health.

Board-Certified OB/GYN & Women's Health Physician

Dr. Palko is a board-certified obstetrician-gynecologist with more than a decade of clinical experience in women's health, pregnancy, reproductive medicine, and hormonal health. As a Fellow of the American College of Obstetricians and Gynecologists, she brings extensive experience caring for women across different stages of life and evaluating complex questions in reproductive and women's health.

Physician, Pathologist & Biomedical Scientist

Dr. Idelevich is a physician, pathologist, and biomedical scientist with decades of experience spanning clinical medicine, disease biology, cancer research, diagnostics, biotechnology, and drug development. His background includes research at the Weizmann Institute of Science and extensive work in pathology and the development of biomedical diagnostic technologies.

Microplastics Researcher & Analytical Chemist

Dr. Cvjetan is an analytical chemist and researcher whose work focuses directly on micro- and nanoplastics, including their behavior, detection, and characterization in aqueous systems. He earned his PhD in Chemistry from ETH Zurich and has published peer-reviewed research spanning micro- and nanoplastic sensing, interfacial chemistry, and advanced analytical methods.

Advisory role only; not medical advice. Advisors are compensated for their time and expertise.

Six active ingredients, three key jobs: Bind, Move, Support.

Expertly Formulated Ingredients

  • 1G Bind Chitosan A fiber shown in research to bind microplastic particles in the gut.
  • 150MG Move Magnesium Oxide Supports regularity and healthy GI transit, keeping things moving.
  • 250MG Move Ginger Root Extract A time-tested digestive botanical for everyday digestive comfort.
  • 215MG Support Sodium Butyrate A short-chain fatty acid that supports the cells lining your gut.
  • 15MG Support Zinc Bisglycinate An essential mineral that supports gut barrier integrity and normal immune function.
  • 2 Billion CFU Support LactoSpore® A spore-forming probiotic that supports digestive balance and a healthy gut microbiome.*

The Supporting Studies

The science is in the ingredients. Below is the published research behind each active ingredient, plus the research on exposure that explains why we built it. These are independent third-party studies on the ingredients themselves, not studies of rmvd, and not all of them used our exact doses or forms. Every reference below links to the paper itself.

  1. Casella C, et al. (2025). Preliminary Study on PCC-Chitosan's Ability to Enhance Microplastic Excretion in Human Stools from Healthy Volunteers. Foods, 14(13), 2190.

    Chitosan · human crossover study, 10 volunteers, single 0.8 g dose with a standardized meal. Fecal microplastic counts rose from 656 to 965 particles, about 45%.

    Chitosan · preliminary human study, 10 volunteers, 0.8 g dose. Not a study of rmvd.

    doi.org/10.3390/foods14132190
  2. Cornelli U, Belcaro G, Casella C. (2026). Reduction in Circulating Microplastics in Humans Following Gastrointestinal Sequestration by Chitosan: A Pilot Controlled Study. Journal of Xenobiotics, 16(3), 92.

    Chitosan · pilot controlled human study with a placebo arm, 11 treated and 10 matched controls, 0.8 g/day for 15 days.

    doi.org/10.3390/jox16030092
  3. Liu D, Shimizu M. (2025). Ingesting chitosan can promote excretion of microplastics. Scientific Reports, 15, 14041.

    Liu D, Shimizu M. (2025). Ingesting chitosan can promote excretion of microplastics. Scientific Reports, 15, 14041.

    doi.org/10.1038/s41598-025-96393-w
  4. Liu D, Morikawa S, Izumi R, Kurozumi S, Kiyose M, Shimizu M. (2026). Effect of different chitosan molecular weights on microplastic excretion. Frontiers in Nutrition, 13, 1869140.

    Chitosan · animal study in rats. Medium and high molecular weight chitosan increased fecal microplastic excretion and reduced retention in the gut.

    doi.org/10.3389/fnut.2026.1869140
  5. Hamer HM, Jonkers D, Venema K, Vanhoutvin S, Troost FJ, Brummer RJ. (2008). Review article: the role of butyrate on colonic function. Alimentary Pharmacology & Therapeutics, 27(2), 104–119.

    Sodium butyrate · mechanism review. Butyrate is the primary energy source for the cells lining the colon and supports epithelial barrier function.

    doi.org/10.3390/foods14132190
  6. Facchin S, Vitulo N, Calgaro M, et al. (2020). Microbiota changes induced by microencapsulated sodium butyrate in patients with inflammatory bowel disease. Neurogastroenterology & Motility, 32(10), e13914.

    Sodium butyrate · human study of the microencapsulated form, in a patient population.

    doi.org/10.1111/nmo.13914
  7. Del Rio EA, Valenzano MC, DiGuilio KM, et al. (2025). Orally Administered Zinc Gluconate Induces Tight Junctional Remodeling and Reduces Passive Transmucosal Permeability Across Human Intestine in a Patient-Based Study. International Journal of Molecular Sciences, 26(17), 8540.

    Zinc · human study, 26 mg zinc gluconate twice daily.

    doi.org/10.3390/ijms26178540
  8. Sturniolo GC, Di Leo V, Ferronato A, D'Odorico A, D'Incà R. (2001). Zinc supplementation tightens "leaky gut" in Crohn's disease. Inflammatory Bowel Diseases, 7(2), 94–98.

    Zinc · human study in a Crohn's disease population, measuring intestinal barrier function.

    pubmed.ncbi.nlm.nih.gov/11383597
  9. Wessels I, Maywald M, Rink L. (2017). Zinc as a Gatekeeper of Immune Function. Nutrients, 9(12), 1286.

    Zinc · mechanism review. The reference behind the normal immune function language on the ingredient card.

    doi.org/10.3390/nu9121286
  10. Majeed M, Nagabhushanam K, Natarajan S, Sivakumar A, Ali F, Pande A, Majeed S, Karri SK. (2016). Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: a double blind randomized placebo controlled pilot clinical study. Nutrition Journal, 15, 21.

    LactoSpore · randomized placebo-controlled human study, 36 participants, 2 billion CFU per day. Same strain and same dose used here.

    doi.org/10.1186/s12937-016-0140-6

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